A medical historian narrates the last century of scientific struggle against an enduring enemy: deadly contagious disease. Ever since the 1918 Spanish influenza pandemic, scientists have dreamed of preventing catastrophic outbreaks of infectious disease. Yet despite a century of medical progress, viral and bacterial disasters continue to take us by surprise, inciting panic and dominating news cycles. From the Spanish flu to the 1924 outbreak of pneumonic plague in Los Angeles to the 1930 “parrot fever” pandemic, through the more recent SARS, Ebola, and Zika epidemics, the last one hundred years have been marked by a succession of unanticipated pandemic alarms. In The Pandemic Century, a lively account of scares both infamous and less known, Mark Honigsbaum combines reportage with the history of science and medical sociology to artfully reconstruct epidemiological mysteries and the ecology of infectious diseases. We meet dedicated disease detectives, obstructive or incompetent public health officials, and brilliant scientists often blinded by their own knowledge of bacteria and viruses. We also see how fear of disease often exacerbates racial, religious, and ethnic tensions―even though, as the epidemiologists Malik Peiris and Yi Guan write, “‘nature’ remains the greatest bioterrorist threat of all.” Like man-eating sharks, predatory pathogens are always present in nature, waiting to strike; when one is seemingly vanquished, others appear in its place. These pandemics remind us of the limits of scientific knowledge, as well as the role that human behavior and technologies play in the emergence and spread of microbial diseases.
The real story of AIDS―how it originated with a virus in a chimpanzee, jumped to one human, and then infected more than 60 million people―is very different from what most of us think we know. Recent research has revealed dark surprises and yielded a radically new scenario of how AIDS began and spread. Excerpted and adapted from the book Spillover, with a new introduction by the author, Quammen's hair-raising investigation tracks the virus from chimp populations in the jungles of southeastern Cameroon to laboratories across the globe, as he unravels the mysteries of when, where, and under what circumstances such a consequential "spillover" can happen. An audacious search for answers amid more than a century of data, The Chimp and the River tells the haunting tale of one of the most devastating pandemics of our time.
Where's your next disease coming from? From anywhere in the world--from overflowing sewage in Cairo, from a war zone in Rwanda, from an energy-efficient office building in California, from a pig farm in China or North Carolina. "Preparedness demands understanding," writes Pulitzer-winning journalist Laurie Garrett, and in this precursor to Betrayal of Trust: The Collapse of Global Public Health, she shows a clear understanding of the patterns lying beneath the new diseases in the headlines (AIDS, Lyme) and the old ones resurgent (tuberculosis, cholera). As the human population explodes, ecologies collapse and simplify, and disease organisms move into the gaps. As globalization continues, diseases can move from one country to another as fast as an airplane can fly.
The next big human pandemic―the next disease cataclysm, perhaps on the scale of AIDS or the 1918 influenza―is likely to be caused by a new virus coming to humans from wildlife. Experts call such an event “spillover” and they warn us to brace ourselves. David Quammen has tracked this subject from the jungles of Central Africa, the rooftops of Bangladesh, and the caves of southern China to the laboratories where researchers work in space suits to study lethal viruses. He illuminates the dynamics of Ebola, SARS, bird flu, Lyme disease, and other emerging threats and tells the story of AIDS and its origins as it has never before been told. Spillover reads like a mystery tale, full of mayhem and clues and questions. When the Next Big One arrives, what will it look like? From which innocent host animal will it emerge? Will we be ready?
The Speckled Monster tells the dramatic story of two parents who dared to fight back against smallpox. After barely surviving the agony of smallpox themselves, they flouted eighteenth-century medicine by borrowing folk knowledge from African slaves and Eastern women in frantic bids to protect their children. From their heroic struggles stems the modern science of immunology as well as the vaccinations that remain our only hope should the disease ever be unleashed again. [more inside]
The most fatal virus known to science, rabies-a disease that spreads avidly from animals to humans-kills nearly one hundred percent of its victims once the infection takes root in the brain. In this critically acclaimed exploration, journalist Bill Wasik and veterinarian Monica Murphy chart four thousand years of the history, science, and cultural mythology of rabies. From Greek myths to zombie flicks, from the laboratory heroics of Louis Pasteur to the contemporary search for a lifesaving treatment, Rabid is a fresh and often wildly entertaining look at one of humankind's oldest and most fearsome foes.
A sweeping new history of how climate change and disease helped bring down the Roman Empire Here is the monumental retelling of one of the most consequential chapters of human history: the fall of the Roman Empire. The Fate of Rome is the first book to examine the catastrophic role that climate change and infectious diseases played in the collapse of Rome's power, a story of nature's triumph over human ambition. Interweaving a grand historical narrative with cutting-edge climate science and genetic discoveries, Kyle Harper traces how the fate of Rome was decided not just by emperors, soldiers, and barbarians but also by volcanic eruptions, solar cycles, climate instability, and devastating viruses and bacteria. [more inside]
The veteran Wall Street Journal science reporter Marilyn Chase’s fascinating account of an outbreak of bubonic plague in late Victorian San Francisco is a real-life thriller that resonates in today’s headlines. The Barbary Plague transports us to the Gold Rush boomtown in 1900, at the end of the city’s Gilded Age. With a deep understanding of the effects on public health of politics, race, and geography, Chase shows how one city triumphed over perhaps the most frightening and deadly of all scourges. [more inside]
It's the summer of 1854, and London is just emerging as one of the first modern cities in the world. But lacking the infrastructure-garbage removal, clean water, sewers-necessary to support its rapidly expanding population, the city has become the perfect breeding ground for a terrifying disease no one knows how to cure. As the cholera outbreak takes hold, a physician and a local curate are spurred to action-and ultimately solve the most pressing medical riddle of their time. [more inside]